사용자 삽입 이미지






















연세암센터 홈페이지



교육 및 임상 경력

1990.3-1991.2: 세브란스 병원 인턴 (의사)
1991.3-1995.2: 세브란스 병원 내과 전공의(내과 전문의)
1995.3-1998.7:연세대 의대 내과학교실, 암센타 전임의 (혈액종양내과 전문의)
1998.8-2000. 7: 미국 텍사스 주립대학 부속 의과대학 암센터
(Cancer Therapy and Research Center)의
전임의 (clinical and research fellow)
2001.3-2006. 2: 연세의대 암전이연구센터 조교수
2006.3- 2007.2: 연세의대 암전이연구센터 부교수
2008.3- : 연세의대 종양내과 부교수
2009.3- : 세브란스병원 피험자보호센터 소장
암전이연구센터 중개연구실장
대한 항암요법 연구회 비뇨 부인암 분과장
2011.3- : 연세의대 종양내과 교수

학술관련경력

대한내과학회
대한암학회
미국암연구학회(AACR) 정회원
미국암학회(ASCO) 정회원

*수상경력
2005 우수 논문 수상 의학, 서울, 한국의 연세 대학
2006 우수 수행 수상, 연세 대학교
2008 우수 연구 논문상(과학 기술 사회의 한국 연맹)

주요 관심분야

위암의 항암약물치료, 신약 임상연구

학력사항

연세대학교 의과대학(1990)
연세대학교 석사(1994)
연세대학교 박사(1997)
미국 의사 자격 획득(1998)


논문

1. Gene transfer effects of thymidine kinase gene of Herpes Simplex type I on ganciclovir cytotoxicity in gastric cancer cell line. Jae Kyung Roh, Soo Jung Gong, Joo Hang Kim, Hyo Dong Uhm, Nae Choon Yoo, Jae Jin Song, Jae Yong Cho, Sun Young Rha, Hyun Cheol Chung, Jin Sik Min, Byung Soo Kim. J Korean Cancer Assoc 30:20-30, 1998

2. Semi-quantitative comparison of terminal restriction fragment length and telomerase in breast cancer for biotherapy. Sun Young Rha, Kyu Hyun Park, Tae Soo Kim, Joo Hang Kim, Jae Kyung Roh, Jin Sik Min, Kyong Sik Lee, Byung Soo Kim, and Hyun Cheol Chung. J Korean Cancer Assoc 30:231-241, 1998

3. Synchronous elevation of soluble intercellular adhesion molecule-1(ICAM-1) and vascular cell adhesion molecule-1(VCAM-1) correlates with gastric cancer progression. Nae Choon Yoo, Hyun Cheol Chung, Hei Cheol Chung, Joon Oh Park, Sun Young Rha, Joo Hang Kim, Jae Kyung Roh, Jin Sik Min, Kyong Sik Lee, Byung Soo Kim, and Sung Hoon Noh. Yonsei Med J 39:27-36, 1998

4. Phase I clinical trial: pharmacokinetics of a novel anthracycline DA-125 and metabolites. Single dose study. JK Roh, SY Rha, CI Lee, KH Lee, JJ Lee, HJ Shim, SD Lee, WB Kim, J Yang, SH Kim, MG Lee. Int J of Clinical Pharmacology and Therapeutics 36:312-319, 1998

5. Different expression patterns of MMP-2 and MMP-9 in breast cancer. Sun Young Rha, Woo Ick Yang, Joo Hang Kim, Jae Kyung Roh, Jin Sik Min, Kyong Sik Lee, Byung Soo Kim, and Hyun Cheol Chung. Oncology Reports 5:875-879, 1998

6. Brain metastasis and leptomeningeal carcinomatosis in breast cancer. Yoon Soo Chang, Jeong Hun Seo, Ruth Lee, Joong Bae Ahn, Kwang Yong Shim, Soo Jung Gong, Hwa Young Lee, Sun Young Rha, Nae Choon Yoo, Chang Ok Suh, Joo Hang Kim, Jae Kyung Roh, Kyong Sik Lee, Jin Sik Min, Byung Soo Kim, Hyun Cheol Chung. J Korean Cancer Assoc 30:464-474, 1998

7. Restoration of wild-type p53 induces chemo-sensitization in the gastric cancer cell line with mutant p53. Ho Young Maeng, Sun Young Rha, Byung Soh Min, Yong Bae Kim, Hyun Joo Kwak, Tae Soo Kim, Kyu Hyun Park, Nae Choon Yoo, Ho Young Lim, Jin Hyuk Choi, Joo Hang Kim, Jae Kyung Roh, Jin Sik Min, Byung Soo Kim, Hyun Cheol Chung. J Korean Cancer Assoc 30:497-507, 1998

8. Effect on malignant phenotypes of gastric cancer cell line after p53 gene transduction. Sun Young Rha, Tae Soo Kim, Sook Jung Jeong, Joong Bae Ahn, Kwang Yong Shim, Soo Jung Gong, Hwa Young Lee, Nae Choon Yoo, Joo Hang Kim, Jae Kyung Roh, Jin Sik Min, Byung Soo Kim, Hyun Cheol Chung. J Korean Cancer Assoc 30:508-520, 1998

9. Telomerase activity and telomere length in various cell lines: Changes of telomerase activity can be another method for chemosensitivity evaluation. Kyu Hyun Park, Sun Young Rha, Chang Han Kim, Tae Soo Kim, Nae Choon Yoo, Joo Hang Kim, Jae Kyung Roh, Sung Hoon Noh, Jin Sik Min, Kyong Sik Lee, Byung Soo Kim, Hyun Cheol Chung. International J Oncology 13:489-495, 1998

10. Alpha-fetoprotein-producing gastric cancer. Ruth Lee, Sun Young Rha, Joong Bae Ahn, Kwang Yong Shim, Jin Hyuk Choi, Ho Young Lim, Nae Choon Yoo, Sung Hoon Noh, Joo Hang Kim, Jae Kyung Roh, Jin Sik Min, Byung Soo Kim, Hyun Cheol Chung. Oncol Rep 5:1179-1184, 1998

11. Genetic change in transforming growth factor-b(TGF-b) receptor type I and type II genes correlates with resistance to TGF-b of human breast cancer cells. Hwa young Lee, Chengshi Quan, Hyun Ja Kwon, Soo Jung Gong, Sun Young Rha, Joong Bae Ahn, Kwang Yong Shim, Nae Choon Yoo, Joo Hang Kim, Jae Kyung Roh, Jin Sik Min, Kyong Sik Lee, Byung Soo Kim, Hyun Cheol Chung. J Korean Cancer Assoc 30:683-691, 1998

12. Microsatellite instability correlate with a prognosis in breast cancer. Hwa Young Lee, Chengshi Quan, Soo Jung Gong, Joon Oh Park, Joong Bae Ahn, Kwang Yong Shim, Sun Young Rha, Nae Choon Yoo, Woo Ick yang, Joo Hang Kim, Jae Kyung Roh, Kyong Sik Lee, Byung Soo Kim, Hyun Cheol Chung. J Korean Cancer Assoc 30:914-920, 1998

13. Plasma TGF-(1 as a tumor marker in breast cancer patients. Hwa Young Lee, Sun Young Rha, Soo Jung Gong, Joong Bae Ahn, Kwang Yong Shim, Joon Oh Park, Hyun Ja Kwon, Nae Choon Yoo, Sook Jung Jeong, Hyun Cheol Chung, Joo Hang Kim, Kyong Sik Lee, Jin Sik Min, Byung Soo Kim, Jae Kyung Roh. J Korean Cancer Assoc 30:935-942, 1998

14. An unusual case of gastric carcinoma with synchronous Non-Hodgkin?s lymphoma. Sung Ha Park, Sun Young Rha, Dae Keun Shim, Hyun Jung Rho, Nae Choon Yoo, Joo Hang Kim, Jae Kyung Roh, Woo Ick Yang, Sung Hoon Noh, Jin Sik Min, Byung Soo Kim, Hyun Cheol Chung. Yonsei Medical Journal 5:463-467, 1998

15. Physiological and pathological changes of plasma urokinase-type plasminogen activator, plasminogen activator inhibitor-1, and urokinase-type plasminogen activator receptor levels in healthy females and breast cancer patients. Chung HC, Rha SY, Park JO, Yoo NC, Kim JH, Roh JK, Min JS, Lee KS, Kim BS, Kim JJ. Breast Cancer Res Treat 49:41-50, 1998

16. Menstrual state should be considered in determining sero-positivity of soluble angiogenic factors in breast. Chung HC, Rha SY, Ahn JB, Shim KW, Yoo NC, Kim JH, Roh JK, Lee KS, Min JS, Kim BS, Kim JJ. Int J Mol Med 2:465-470, 1998

17. Effects of Interleukin-2 transduction into the human hepatoma cell lines using retroviral vector. Kim JH, Gong SJ, Yoo NC, Lee H, Shin DH, Uhm HD, Jeong SJ, Cho JY, Rha SY, Kim YS, Chung HC, Roh JK, Min JS, Kim BS. Oncol Rep 6:49-54, 1999

18. Combined pre-operative chemotherapy with intra-arterial cisplatin and continuous intravenous adriamycin for high grade osteosarcoma. Rha SY, Chung HC, Gong SJ, Shim KY, Ahn JB, Yang WI, Shin KH, Yoo NC, Kim JH, Roh JK, Lee CI, Kim BS. Oncol Rep 6:631-637, 1999

19. Clinical relevance of urokinase-type plasminogen activator (uPA), uPA receptor, plasminogen activator inhibitor-1 co-expression from tissue and serum of breast cancer as targets of biotherapy. Sun Young Rha, Joon Oh Park, Soo Jung Gong, Se Ho Park, Nae Choon Yoo, Woo Ick Yang, Jae Kyung Roh, Jin Sik Min, Kyong Sik Lee, Byung Soo Kim, Hyun Cheol Chung. J Korean Cancer Assoc 31:256-266, 1999

20. Midkine expression in cell lines and tumor tissues of glioblastoma multiforme. Jin Woo Chang, Sun Young Rha, Joon Oh Park, Soo Jung Gong, Se Ho Park, Nae Choon Yoo, Woo Ick Yang, Jae Kyung Roh, Jin Sik Min, Kyong Sik Lee, Byung Soo Kim, Hyun Cheol Chung. J Korean Cancer Assoc 31:617-626, 1999

21. The efficacy of pre-operative chemotherapy with intra-arterial cisplatin and continuous intravenous adriamycin for high grade osteosarcoma. Rha SY, Gong SJ, Chung HC, Shim KY, Ahn JB, Yoo NC, HC Chung, Kim JH, Roh JK, JS Min, Kim BS, Shin KH, Yang WI, CI Lee. J Korean Cancer Assoc 31:134-143, 1999

22. Efficacy of gemcitabine chemotherapy in advanced non-small cell lung cancer (NSCLC): A phase II study. Chang HJ, Ahn JB, Lee JG, Shim KY, Rha SY, Kim SK, Chang J, Kim SK, Lee WY, Yoo NC, Chung HC, Roh JK, Kim BS, Choi SJ, Kim TW, Suh CW, Kim JH. J Korean Cancer Assoc 31:523-532, 1999

23. Modulation of biological phenotypes for tumor growth and metastasis by target-specific biological inhibitors in gastric cancer. Rha SY, Noh SH, Kim TS, Yoo NC, Roh JK, Min JS, Kim BS, Kim MY, Chung HC. Int J Mol Med 4:203-212, 1999

24. Changes of telomerase and telomere lengths in paired normal and cancer tissues of breast. Rha SY, KH Pak, Kim TS, Yoo NC, Yang WI, Roh JK, Min JS, Lee KS, Kim BS, Choi JH, Lim HY, Chung HC. Int J Oncol 15:839-845, 1999

25. Clinical significance of urokinase-type plasminogen activator receptor (uPAR) expression in breast cancer tissues. Gong SJ, Rha SY, Chung HC, Park JO, Yoo NC, Roh JK, Yang WI, Lee KS, JS Min, Kim BS, Chung HC. J Korean Cancer Assoc 32:53-59, 2000

26. Effect of telomere and telomerase interactive agents on human tumor and normal cell lines, Rha SY, Izbicka E, Lawrence R, Davidson K, Sun D, Moyer MP, Roodman GD, Hurley L, Von Hoff DD. Clinical Cancer Research 6:987-993, 2000

27. Correlation of tissue and blood plasminogen activation system in breast cancer. Rha SY, Yang WI, Gong SJ, Kim JJ, Yoo NC, Roh JK, Min JS, Lee KS, Kim BS, Chung HC. Cancer Letter 150:137-145, 2000

28. Effect of 5-FU plus leucovorin for adjuvant chemotherapy according to dose related factors in colon cancer. Shim KW, Ahn JB, Jung HC, Park JO, Yoo NC, Rha SY, Roh JK, Kim BS, Kim NK, Min JS, Chung HC. Korean Journal of Medicine 59:290-299, 2000

29. Tissue urokinase-type plasminogen activator receptor levels in breast cancer. Gong SJ, Rha SY, Chung HC, Yoo NC, Roh JK, Yang WI, Lee KS, Min JS, Kim BS, Chung HC. International J Mol Medicine 6:301-305, 2000

30. Application of Gabexate Mesylate IC against MMP - 9 Using ex vivo Model in Gastric Cancer: Prognostic Factor and Selection Criteria for Anti - MMP Treatment. Moon YW, Yang H, Jung HC, Rha SY, Kim TS, Yoo NC, Noh SH, Roh JK, Min JS, Kim BS, Chung HC. J Korean Cancer Assoc. 2000 Feb;32(1):7-18.

31. Adjuvant 5-fluorouracil plus doxorubicin in D2-3 resected gastric carcinoma: 15-year experience at a single institute. HC Jeung, SY Rha, SH Noh, JS Min, BS Kim, HC Chung. Cancer 91:2016-2025, 2001

32. Monthly 5-days 5-fluorouracil and low-dose leucovorin for adjuvant chemotherapy in colon cancer. Ahn JB, Shim KY, Jeung HC, Rha SY, Yoo NC, Kim NK, Roh JK, Min JS, Kim BS, Chung HC. Cancer Letter 2001; 167: 215-224

33. Efficacy of pre- and posoperative chemotherapy in patients with osteosarcoma of the extremities. JH Sohn, SY Rha, HC Jeung, HJ Shin, YS Goo, HC Chung, WI Yang, SB Hahn, KH Sin, JS Min, BS Kim, JK Roh, WI Jang. Cancer Research and Treatment 2001:33:391-397

34. Design and synthesis of fluoroquinophenoxazines that interact with human telomeric G-quadruplexes and their biologic effects. W Duan, A Rangan, H Vankayalapati, MY Kim, Q Zeng, D Sun, H Han, OY Fedoroff, D Nishioka, SY Rha, E Izbicka, DD Von Hoff, LH Hurley.

Mol Cancer Therapeutics 2001:1:103-120

35. Treatment of advanced gastric cancer by palliative gastrectomy, cytoreductive therapy and postoperative intraperitoneal chemotherapy. HC Jeung, SY Rha, WI Jang, SH Noh, HC Chung. Br J Surg 2002:89:460-466

36. Changes of telomerase activity and proliferation by inhibition of reverse transcriptase activity in human cancer cell. HJ Ji, KH Park, TS Kim, SY Rha, NC Yoo, WI Jang, HC Chung. Cancer Research and Treatment 2002:34:223-233.

37. Biological phenotype determination with ex vivo model in gastric cancer for matrix-metalloproteinase inhibitor treatment. Rha SY, Jeung HC, Roh JK, Kim JJ, Noh SH, Min JS, Kim BS, Chung HC. Int J Mol Med. 2002 Sep;10(3):251-6.

38. Metastatic model of human gastric cancer by orthotopic transplantation. Kim YI, Hyung WJ, Chung HC, Lee MH, Rha SY, Rho JK, Noh SH. J Kor Sur Soc 2002:63;30-34.

39. Microarray-based Analysis of Anti-angiogenic Activity of Demethoxycurcumin on Human Umbilical Vein Endothelial Cells: Crucial Involvement of the Down-regulation of Matrix Metalloproteinase. Kim JH, Shim JS, Lee SK, Kim KW, Rha SY, Chung HC, Kwon HJ. Jpn J Cancer Res. 2002 Dec;93(12):1378-85.

40. Analysis of HPV-16 E6-related gene expression using cDNA microarray. Myeong J, Rha SY, Lee MJ, Um SJ, Namkoong SE, Park JS. Korean J Obstet Gynecol. 2002 Dec;45(12):2280-2288.

41. A phase II study of gemcitabine monotherapy in breast cancer patients refractory to anthracycline and taxane. Park JY, Kim C, Sohn JH, Kim YT, Rha SY, Jang WI, Kim GE, Chung HC. Cancer Res Treat 2002:34:274-279.

42. Genome-scale analysis of resveratrol-induced gene expression profile in human ovarian cancer cells using a cDNA microarray. Yang SH, Kim JS, Oh TJ, Kim MS, Lee SW, Woo SK, Cho HS, Choi YH, Kim YH, Rha SY, Chung HC, An SW. Int J Oncol. 2003 ;22:741-50.

43. Infusional fluorouracil, etoposide, and cisplatin (FEP) in advanced and relapsed gastric cancer. Sohn JH, Jeung HC, Shin HJ, Rha SY, Roh JK, Noh SH, Min JS, Kim BS, Jang WI, Chung HC. Am J Clin Oncol. 2003 Apr;26(2):203-9.

44. Regions of allelic imbalance in the distal portion of chromosome 12q in gastric cancer. Schneider BG, Rha SY, Chung HC, Bravo JC, Mera R, Torres JC, Plaisance KT Jr, Schlegel R, McBride CM, Reveles XT, Leach RJ. Mol Pathol. 2003 Jun;56(3):141-149.

45. Paclitaxel and Cisplatin Combination Chemotherapy in Pretreated Breast Cancer. Sohn JH, Kim YT, Rha SY, Yoo NC, Roh JK, Kim BS, Suh CO, Kim GE, Jang WI, Chung HC. Cancer Res Treat. 2003 Jun;35(3):267-273.

46. A case of paraneoplastic nephritic syndrome in a patients with ovarian carcinoma. Kim YT, Rha SY, Shim CY, Sohn JH, Kim C, Yu NC, Chung HC, Kim JH, Han DS, Kim BS, Roh JK. Yonsei Medical Journal 2003:44:539-543

47. Infusional 5-fluorouracil, leucovorin and docetaxel in advanced gastric cancer. Kim YT, Sohn JH, Kim SH, Rha SY, Kim C, Roh JK, Kim BS, Jang WI, Chung CH. Cancer Research and Treatment 2003:35:123-129

48. Increased expression of matrix metalloproteinase 9 correlates with poor prognostic variables in renal cell carcinoma. Cho NH, Shim HS, Rha SY, Kang SH, Hong SH, Choi YD, Hong SJ, Cho SH. Eur Urol. 2003 Nov;44(5):560-6.

49. cDNA microarray experiment: Design issues in early stage and the need of normalization. BS Kim, SH Lee, SY Rha, CH Chung. Cancer Res Treat 2003:35(6): 533 -540

50. The pattern of gene copy number changes in bilateral breast cancer surveyed by cDNA microarray-based comparative genomic hybridization. Seo MY, Rha SY, Yang SH, Kim SC, Lee GY, Park CH, Yang WI, Ahn JB, Park BW, Chung HC. Int J Mol Med. 2004 Jan;13(1):17-24.

52. Expression of matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in intraductal and nonintraductal growth type of cholangiocarcinoma. Jo Chae K, Rha SY, Oh BK, Koo JS, Kim YJ, Choi J, Park C, Park YN. Am J Gastroenterol. 2004 Jan;99(1):68-75.

53. In silico screening for angiogenesis-related genes in rat astrocytes. SY Kim, SW Lee, SY You, SY Rha, KW Kim. Genomics and Informatics 2004:2(1) 36-44

54. Fabrication of high quality cDNA microarray using a small amount of cDNA. Park CH, Jeong HJ, Jung JJ, Lee GY, Kim SC, Kim TS, Yang SH, Chung HC, Rha SY. Int J Mol Med. 2004 May;13(5):675-9.

55. Comparison of the Efficacy of Urine Cytology and Fluorescence in Situ Hybridization (FISH) for the Detection of Bladder Urothelial Carcinoma. Choi YD, Cho NH, Chang SY, Rha SY, Chung HC, Park K. Korean J Urol. 2004 May;45(5):410-415.

56. Lack of Correlation Between P-glycoprotein and Chemotherapy Resistance in Nasal NK/T-cell Lymphomas. Kim GE, Yang WI, Lee SW, Rha SY, Chung HC, Kim JH, Cho JH, Suh CO, Yoo NC, Roh JK, Hahn JS. Leuk Lymphoma. 2004;45(9):1857-1864.

57. Spearman's footrule as a measure of cDNA microarray reproducibility. Kim BS, Rha SY, Cho GB, Chung HC. Genomics. 2004 Aug;84(2):441-8.

58. Phase I and pharmacokinetic study of the oral fluoropyrimidine S-1 on a once-daily-for-28-day schedule in patients with advanced malignancies. Chu QS, Hammond LA, Schwartz G, Ochoa L, Rha SY, Denis L, Molpus K, Roedig B, Letrent SP, Damle B, DeCillis AP, Rowinsky EK. Clin Cancer Res. 2004 Aug 1;10(15):4913-21

59. Growth inhibitory effects of trastuzumab and chemotherapeutic drugs in gastric cancer cell lines. Gong SJ, Jin CJ, Rha SY, Chung HC. Cancer Lett. 2004 Oct 28;214(2):215-24.

60. Statistical method of determining a cut off value between normal and disease group. Inyoung Kim, Yeon-ho Coi, Hyun Cheol Chung, Sun Young Rha, Byung Soo Kim. Bull Informatics and Cybernetics 36:63-72, 2004

61. Analysis of Criteria for Tumor Response after Preoperative Chemoradiation Therapy for Locally Advanced Rectal Cancer: Correlation between Tumor Volume Reduction and Histopathologic Downstaging. Kim NK, Pyo HR, Baik SH, Lee KY, Sohn SK, Cho CH, Rha SY, Chung HC. J Korean Soc Coloproctol. 2004 Oct;20(5):296-302.

62. Phase I trial of a murine antibody to MUC1 in patients with metastatic cancer: evidence for the activation of humoral and cellular antitumor immunity. de Bono JS, Rha SY, Stephenson J, Schultes BC, Monroe P, Eckhardt GS, Hammond LA, Whiteside TL, Nicodemus CF, Cermak JM, Rowinsky EK, Tolcher AW. Ann Oncol. 2004 Dec;15:1825-33.

63. Different role of functional domains of hTR in DNA binding to telomere and telomerase reconstruction. Yeo M, Rha SY, Jeung HC, Shen XH, Yang SH, An SW, Roh JK, Chung HC. FEBS Lett. 2005 Jan 3;579(1):127-32.

64. Determination of genes related to gastrointestinal tract origin cancer cells using a cDNA Microarray. TM Kim, HJ Jeong, MY Seo, SC Kim, G Cho, CH Park, TS Kim, KH Park, HC Chung, SY Rha . Clinical Cancer Research 2005 Jan 1;11(1):79-86.

65. Gene copy number change events at chromosome 20 and their association with recurrence in gastric cancer patients. Yang SH, Seo MY, Jeong HJ, Jeung HC, Shin J, Kim SC, Noh SH, Chung HC, Rha SY. Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):612-20.

66. Statistical methods of translating microarray data into clinically relevant diagnostic information in colorectal cancer. Kim BS, Kim I, Lee S, Kim S, Rha SY, Chung HC. Bioinformatics. 2005 Feb 15;21(4):517-28

67. Preoperative chemoradiation followed by total mesorectal excision for locally advanced rectal cancer: Oncologic outcomes according to pathologic T and N stage. NK Kim, SH Paik, KY Lee, SK Shon, CH Cho, JS Min, JS Seong, HC Chung, SY Rha. J Korean Surg Soc 2005:68:218-223

68. Attenuation of telomerase activity by hammerhead ribozyme targeting human telomerase RNA induces growth retardation and apoptosis in human breast tumor cells.

Yeo M, Rha SY, Jeung HC, Hu SX, Yang SH, Kim YS, An SW, Chung HC. Int J Cancer. 2005 Apr 10;114(3):484-9.

69. Gemcitabine monotherapy as salvage chemotherapy in heavily pretreated metastatic breast cancer. Rha SY, Moon YH, Jeung HC, Kim YT, Sohn JH, Yang WI, Suh CO, Kim GE, Roh JK, Chung HC. Breast Cancer Res Treat. 2005 Apr;90(3):215-21.

70. Gastrointestinal stromal tumor of rectum: A report of 7 cases. SH Paik, NK Kim, CH Lee, KY Lee, SK Sohn, CH Cho, HG Kim, HY Pyo, Rha SY, Chung HC. J Korean Surg Soc. 2005:68:117-122.

71. Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents. Jeung HC, Che XF, Haraguchi M, Furukawa T, Zheng CL, Sumizawa T, Rha SY, Roh JK, Akiyama S. Biochem Pharmacol. 2005 Jul 1;70(1):13-21.

72. Rapid prenatal diagnosis for chromosomal aneuploidy using cDNA microarray-based comparative genomic hybridization. YH Yang, SY Rha, YW Jung, ES Yang, KY Lee, CH Park, IK Kim, HS Hwang, YW Park, JK Roh. Korean Journal of Obstetrics & Gynecology 2005: 48:1621-1634.

73. Neoadjuvant chemotherapy with infusional 5-fluorouracil, adriamycin and cyclophosphamide (iFAC) in locally advanced breast cancer: an early response predicts good prognosis. Moon YW, Rha SY, Jeung HC, Yang WI, Suh CO, Chung HC. Ann Oncol. 2005 Nov;16(11):1778-85.

74. Cyclic Induction of Senescence with Intermittent AZT Treatment Accelerates Both Apoptosis and Telomere Loss. Ji HJ, Rha SY, Jeung HC, Yang SH, An SW, Chung HC. Breast Cancer Res Treat 2005 Oct;93(3):227-36.

75. Quantitative detection of telomerase activity by real-time TRAP assay in the body fluids of cancer patients. Shim WY, Park KH, Kim YT, Kim TS, Hyung WJ, An SH, Yang SH, Noh SH, Chung HC, Rha SY. Int J Mol Med. 2005 Nov;16(5):857-63.

76. A Phase II Study of Infusional 5-Fluorouracil and Low-Dose Leucovorin with Docetaxel for Advanced Gastric Cancer. Jeung HC, Rha SY, Kim YT, Noh SH, Roh JK, Chung HC.

Oncology. 2006 Jan 27;70(1):63-70.

77. Intermediate dose 5-Fluorouracil-induced encephalopathy. Kim YA, Chung HC, Choi HJ, Rha SY, Seong JS, Jeung HC. Jpn J Clin Oncol. 2006 Jan;36(1):55-9.

78. Systematic analysis of cDNA microarray-based CGH. Park CH , Jeong HJ , Choi YH , Kim SC , Jeong HC , Park KH , Lee GY , Kim TS ,Yang SW ,Ahn SW ,Kim YS ,Rha SY ,Chung HC. Int J Mol Med. 2006 Feb;17(2):261-7.

79. A case of toxoplasmosis mimicking systemic recurrence in a patient treated with breast cancer. BK Kim, BC Cho, YW Lee, HS Chung, HC Jeung, SY Rha, HC Chung. Korean J Med 2006:71:1108-113

80. Effect of missing values in detecting differentially expressed genes in a cDNA microarray experiment. Byung Soo Kim, Sun Young Rha, Bioinformatics and Biosystems, 2006:1:67

81. Alteration of hTERT full-length variant expression level showed different gene expression profiles and genomic copy number changes in breast cancer. Rha SY, Jeung HC, Yang WI, Kim JJ, Oh TJ, An SW, Chung HC. Oncol Rep. 2006 Apr;15(4):749-55.

82. Ribonucleotide reductase M1 (RRM1) 2464G>A polymorphism shows an association with gemcitabine chemosensitivity in cancer cell lines. Kwon WS, Rha SY, Choi YH, Lee JO, Park KH, Jung JJ, Kim TS, Jeung HC, Chung HC. Pharmacogenet Genomics. 2006 Jun;16(6):429-38. (5.882)

83. A phase II trial of weekly fractionated irinotecan and cisplatin for advanced gastric cancer. Jeung HC, Rha SY, Noh SH, Roh JK, Chung HC.Cancer Chemother Pharmacol. 2006 Jun 13; ; [Epub ahead of print]

84. Irofulven as first line therapy in recurrent or metastatic gastric cancer: a phase II multicenter study by the Cancer Therapeutics Research Group (CTRG). Yeo W, Boyer M, Chung HC, Ong SY, Lim R, Zee B, Ma B, Lam KC, Mo FK, Ng EK, Ho R, Clarke S, Roh JK, Beale P, Rha SY, Jeung HC, Soo R, Goh BC, Chan AT. Cancer Chemother Pharmacol. 2006 Jun 17; [Epub ahead of print]

85. The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation. Seng TJ, Low JS, Li H, Cui Y, Goh HK, Wong ML, Srivastava G, Sidransky D, Califano J, Steenbergen RD, Rha SY, Tan J, Hsieh WS, Ambinder RF, Lin X, Chan AT, Tao Q. Oncogene. 2006 Jul 24; [Epub ahead of print]

86. Significant gene selection using integrated microarray data set with batch effect .KY Kim, HC Chung, HC Jeung, JH Shin, TS Kim, SY Rha. Genomics and Informatics 2006:4 (3) 110-117

87. Induction of cell apoptosis in non-small cell lung cancer cells by cyclin A1 small interfering RNA. Cho NH, Choi YP, Moon DS, Kim H, Kang S, Ding O, Rha SY, Yang YJ, Cho SH. Cancer Science 2006;97(10):1082-92

88. Statistical Method for Implementing the Experimenter Effect in the Analysis of Gene Expression Data. Y Kim, SY Rha, BS Kim 한국 통계학회 2006; 13;3

89. Long-term survival after surgical resection for liver metastasis from gastric cancer: Two case reports. JK Lim, JB Ahn, SH Cheon, H Chang, JY Jung, SY Rha, JK Roh, SH Noh, HG Kim, HC Chung, HC Jeung . Cancer Res Treatment 2006: 38(3)

90. Activation of Hypoxia-Inducible Factor-1{alpha} Is Necessary for Lysophosphatidic Acid-Induced Vascular Endothelial Growth Factor Expression. Lee J, Park SY, Lee EK, Park CG, Chung HC, Rha SY, Kim YK, Bae GU, Kim BK, Han JW, Lee HY. Clin Cancer Res. 2006 Nov 1;12(21):6351-8.

91. A comparative study of volumetric analysis, histopathologic downstaging, and tumor regression grade in evaluating tumor response in locally advanced rectal cancer following preoperative chemoradiation. Kim NK, Baik SH, Min BS, Pyo HR, Choi YJ, Kim H, Seong J, Keum KC, Rha SY, Chung HC. Int J Radiat Oncol Biol Phys. 2006 Nov 1

92. A phase II trial of S-1 monotherapy in metastatic colorectal cancer after failure of irinotecan- and oxaliplatin-containing regimens. Jeung HC, Rha SY, Cho BC, Yoo NC, Roh JK, Roh WJ, Chung HC, Ahn JB. British J Cancer 2006 :95:1637-41

93. Prognostic impact of resection margin involvement after extended (D2/D3) gastrectomy for advanced gastric cancer: A 15-year experience at a single institute. Cho BC, Jeung HC, Choi HJ, Rha SY, Hyung WJ, Cheong JH, Noh SH, Chung HC. J Surg Oncol. 2006 Dec 27

94. Identification of genes with correlated patterns of variations in DNA copy number and gene expression level in gastric cancer. Yang S, Jeung HC, Jeong HJ, Choi YH, Kim JE, Jung JJ, Rha SY, Yang WI, Chung HC. Genomics. 2007 Jan 15

95. In vitro pharmacogenomic database and chemosensitivity predictive genes in gastric cancer. Jung JJ, Jeung HC, Chung HC, Lee JO, Kim TS, Kim YT, Noh SH, Rha SY. Genomics. 2009 Jan;93(1):52-61.

96. Promoter methylation of the Wnt/beta-catenin signaling antagonist Dkk-3 is associated with poor survival in gastric cancer. Yu J, Tao Q, Cheng YY, Lee KY, Ng SS, Cheung KF, Tian L, Rha SY, Neumann U, R?cken C, Ebert MP, Chan FK, Sung JJ. Cancer. 2009 Jan 1;115(1):49-60.

97. Association of the ABCB1 gene polymorphisms 2677G>T/A and 3435C>T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients. Ann Oncol. Chang H, Rha SY, Jeung HC, Im CK, Ahn JB, Kwon WS, Yoo NC, Roh JK, Chung HC. 2009 Feb;20(2):272-7.

98. Effect of being overweight on postoperative morbidity and long-term surgical outcomes in proximal gastric carcinoma. Oh SJ, Hyung WJ, Song J, Rha SY, Chung HC, Choi SH, Noh SH. J Gastroenterol Hepatol. 2009 Mar;24(3):475-9

99. Postoperative adjuvant chemotherapy of gastric cancer: scrutiny into the clinical evidence based on quality assessment of medical literature of randomized controlled trials. Jeung HC, Rha SY, Shin SJ, Ahn JB, Roh JK, Park CH, Noh SH, Chung HC. Cancer Chemother Pharmacol. 2009 Apr;63(5):919-27.

100. G-T haplotype (2677G>T/A and 3435C>T) of ABCB1 gene polymorphisms is associated with ethnic differences to paclitaxel sensitivity in cancer cells with different gene expression pattern. Kwon WS, Rha SY, Jeung HC, Ahn JB, Jung JJ, Noh SH, Chung HC. Cancer Lett. 2009 277:155-63

101. The effect of spleen-preserving lymphadenectomy on surgical outcomes of locally advanced proximal gastric cancer. Oh SJ, Hyung WJ, Li C, Song J, Kang W, Rha SY, Chung HC, Choi SH, Noh SH; J Surg Oncol. 2009 :99:275-80

102. DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers. Ying J, Poon FF, Yu J, Geng H, Wong AH, Qiu GH, Goh HK, Rha SY, Tian L, Chan AT, Sung JJ, Tao Q. Br J Cancer. 2009:100: 663-9.

103. Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma. HR Kim, SY Rha, SH Cheon, JK Roh, YN Park, NC Yoo, Annals Oncol 2009:20:780-7.

104. Copy number changes can be a predictor for hemoglobin reduction after S-1 monotherapy in gastric cancer. Jeung HC, Rha SY, Park CH, Im CK, Shin SJ, Ahn JB, Noh SH, Roh JK, Chung HC. Int J Oncol. 2009 Mar 34(3):787-96.

105. Prediction of high-risk patients by genome-wide copy number alterations from remaining cancer after neoadjuvant chemotherapy and surgery. Rha SY, Jeung HC, Seo MY, Kim SC, Yang WI, Moon YW, Chung HC. Int J Oncol. 2009 Mar;34(3):837-46.

106. Subtelomeric DNA methylation and telomere length in human cancer cells. Lee ME, Rha SY, Jeung HC, Chung HC, Oh BK. Cancer Lett. 2009 Aug 18;281(1):82-91.

107. Benefits of recurrent colonic stent insertion in a patient with advanced gastric cancer with carcinomatosis causing colonic obstruction. Park S, Shin SJ, Ahn JB, Jeung HC, Rha SY, Lee SK, Chung HC. Yonsei Med J. 2009 Apr 30;50(2):296-9.

108. Prediction of Recurrence of Early Gastric Cancer After Curative Resection. Lai JF, Kim S, Kim K, Li C, Oh SJ, Hyung WJ, Rha SY, Chung HC, Choi SH, Wang LB, Noh SH. Ann Surg Oncol. 2009:16:1896-902.

109. Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer. Hu XT, Zhang FB, Fan YC, Shu XS, Wong AH, Zhou W, Shi QL, Tang HM, Fu L, Guan XY, Rha SY, Tao Q, He C. Oncogene. 2009:28:2466-75.

110. Phase I and pharmacokinetic study of cisplatin and troxacitabine administered intravenously every 28 days in patients with advanced solid malignancies. Lin CC, Beeram M, Rowinsky EK, Takimoto CH, Ng CM, Geyer CE Jr, Denis LJ, De Bono JS, Hao D, Tolcher AW, Rha SY, Jolivet J, Patnaik A. Cancer Chemother Pharmacol. 2009 May 16. [Epub ahead of print]

111. Prognostic index reflecting genetic alteration related to disease-free time for gastric cancer patient. Kim M, Rha SY. Oncol Rep. 2009 Aug;22(2):421-31.

112. A phase I pharmacokinetic and pharmacodynamic study of CKD-732, an antiangiogenic agent, in patients with refractory solid cancer. Shin SJ, Jeung HC, Ahn JB, Rha SY, Roh JK, Park KS, Kim DH, Kim C, Chung HC. Invest New Drugs. 2009 Jul 8. [Epub ahead of print]

113. Increments of alpha-dystroglycan expression in liver metastasis correlate with poor survival in gastric cancer. Moon YW, Rha SY, Zhang X, Jeung HC, Yang WI, Kwon O, Jeong JH, Cheon SH, Yoo NC, Chung HC. J Surg Oncol. 2009 Jul 13. [Epub ahead of print]

114. Circulating endothelial progenitor cells (EPC) for tumor vasculogenesis in gastric cancer patients. Ahn JB, Rha SY, Shin SJ, Jeung HC, Kim TS, Zhang X, Park KH, Noh SH, Roh JK, Chung HC. Cancer Lett. 2009 Jul 18. [Epub ahead of print]

115. A weighted sample size for microarray datasets that considers the variability of variance and multiplicity

Ki-Yeol Kim1, Hyun Cheol Chung2, 3, 4 and Sun Young Rha. Journal of Bioscience and Bioengineering 2009:108:252-258 (SCI, IF 1.702)

116: Identification of significant regional genetic variations using continuous CNV values in aCGH data.

Kim KY, Lee GY, Kim J, Jeung HC, Chung HC, Rha SY. Genomics. 2009 Aug 19. [Epub ahead of print]

117: Treatment outcomes of sunitinib treatment in advanced renal cell carcinoma patients: a single cancer center experience in Korea. Hong MH, Kim HS, Kim C, Ahn JR, Chon HJ, Shin SJ, Ahn JB, Chung HC, Rha SY. Cancer Res Treat. 2009 Jun;41(2):67-72.

118: Prognosis of pN3 Stage Gastric Cancer. Ahn JR, Jung M, Kim C, Hong MH, Chon HJ, Kim HR, Jeung HC, Hyung WJ, Lee SS, Chung HC, Noh SH, Rha SY. Cancer Res Treat. 2009 Jun;41(2):73-9.

119: A Phase II Study of a Combined Biweekly Irinotecan and Monthly Cisplatin Treatment for Metastatic or Recurrent Gastric Cancer. Im CK, Rha SY, Jeung HC, Ahn JB, Shin SJ, Noh SH, Roh JK, Chung HC.

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120. Adenocarcinoma of the small bowel at a single Korean institute: management and prognosticators.

Moon YW, Rha SY, Shin SJ, Chang H, Shim HS, Roh JK. J Cancer Res Clin Oncol. 2009 Sep 16. [Epub ahead of print]

121. The clinical significance of ascetic fluid CEA in advanced gastric cancer with ascites. M Jung, HC Jeung, SS Lee, JY Park, S Kong, SH Lee, SH Noh, HC Chung, SY Rha. J Cancer Res Clin Oncol. 2009 Sep


Clinical significance of urokinase-type plasminogen activator receptor (uPAR) expression in breast cancer tissues
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Correlation of tissue and blood plasminogen activation system in breast cancer
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 150 0:137~145,2000


Effect of 5-FU plus leucovorin for adjuvant chemotherapy according to dose related factors in colon cancer
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Effect of telomere and telomerase interactive agents on human tumor and normal cell lines
CLINICAL CANCER RESEARCH 6 0:987~993,2000


Tissue urokinase-type plasminogen activator receptor levels in breast cancer
International J Mol Medicine 6 0:301~305,2000


Adjuvant 5-fluorouracil plus doxorubicin in D2-3 resected gastric carcinoma: 15-year experience at a single institute.
CANCER 91 11:2016~2025,2001


Design and synthesis of fluoroquinophenoxazines that interact with human telomeric G-quadruplexes and their biologic effects.
Mol Cancer Therapeutics 1 0:103~120,2001


Efficacy of Pre - and Postoperative Chemotherapy in Patients with Osteosarcoma of the Extremities
대한암학회지 33 6:520~526,2001


Monthly 5-days 5-fluorouracil and low-dose leucovorin for adjuvant chemotherapy in colon cancer.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 167 2:215~224,2001


Efficacy of Pre- and Postoperative Chemotherapy in Patients with Osteosarcoma of the Extremities
Cancer Research and Treatment 33 6:520~526,2001


A phase II study of gemcitiabine monotherapy in breast cancer patients refractory to anthracycline and taxane
CANCER RESEARCH AND TREATMENT 34 4:274~279,2002


Biological phenotype determination with ex vivo model in gastric cancer for matrix-metalloproteinase inhibitor treatment.
Int J Mol Oncol 10 3:251~256,2002


cDNA microarray를 이용한 HPV-16 E6와 연관된 유전자의 발현 분석.
대한산부인과학회지(KoreanJournalOfObstetricsAndGynecology) 45 0:2183~2191,2002


Changes of telomerase activity and proliferation by inhibition of reverse transcriptase activity in human cancer cell.
Cencer Research and Treatment 34 0:223~233,2002


Metastatic model of human gastric cancer by orthotopic transplantation
대한외과학회지 63 0:30~34,2002


Treatment of advanced gastric cancer by palliative gastrectomy, cytoreductive therapy and postoperative intraperitoneal chemotherapy.
BRITISH JOURNAL OF SURGERY 89 4:460~466,2002


cDNA microarray experiment: disign issues in early stage and the need of normalization
CANCER RESEARCH AND TREATMENT 35 6:533~540,2003


A case of paraneoplastic nephrotic syndrome in a patient with ovarian carcinoma
YONSEI MEDICAL JOURNAL 44 3:539~543,2003


Genome-scale analysis of resveratrol-induced gene expression profile in human ovarian cancer cells using a cDNA microarray
Int J Oncology 22 0:741~750,2003


Increased expression of matrix metalloproteinase 9 correlates with poor
EUROPEAN UROLOGY 44 5:560~566,2003


Infusional 5-flurouracil, leucovorin and docetaxel in advanced gastric cancer
CANCER RESEARCH AND TREATMENT 35 0:123~129,2003


Infusional Fluorouracil, Etoposide, and Cisplatin(FEP) in Advanced and Relapsed Gastric Cancer
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS 26 2:203~209,2003


Paclitaxel and Cisplatin Combination Chemotherapy
CANCER RESEARCH AND TREATMENT 35 0:267~273,2003


Regions of allelic imbalance in the distal portion of chromosome 12q in gastric cancer
MOLECULAR PHARMACOLOGY 56 0:141~149,2003


국소 진행된 직장암의 수술 전 화학방사선 요법 치료 후 종양반응 분석: 종양체적 변화와 병리조직학적 병기하강과의 상관관계 분석
대한대장항문학회지(Journal Of The Korean Society Of Coloproctology) 20 5:296~302,2004


In Silico Screening for Angiogenesis-Related Genes in Rat Astrocytes
GENOMICS & INFORMATICS 2 1:36~44,2004


Phase I and Pharmacokinetic study of the oral fluoropyrimidine S-1 on a Once-Daily-for-28-day schedule in patients with advanced malignancies
CLINICAL CANCER RESEARCH 10 15:4913~4921,2004


Lack of correlation between P-glycoprotein and chemotherapy resistance in nasal NK/T-cell lymphomas
LEUKEMIA & LYMPHOMA 45 9:1857~1864,2004


Statistical methods of determining a cut off value between normal and disease groups
Bulletin of Informatics and Cybernetics 36:63~72,2004


직장에 발생한 위장관 간질종양 7예
대한외과학회지 68 2:117~122,2005


Gemcitabine monotherapy as salvage chemotherapy in heavily pretreated metastatic breast cancer
BREAST CANCER RESEARCH AND TREATMENT 90 3:215~221,2005


진행된 직장암에서 수술 전 화학 방사선 요법 후 전직장간막절제술의 임상적 고찰: 병리학적 T 병기와 N 병기하강에 따른 임상 결과 분석
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직장암에서 전 직장간막 절제술 후 측방절제연이 예후에 미치는 영향
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Cyclic induction of senescence with intermittent AZT treatment accelerates both apoptosis and telomere loss
BREAST CANCER RESEARCH AND TREATMENT 93:227~236,2005


Determination of genes related to gastrointestinal tract origin cancer cells using a cDNA microarray
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Gene copy number change events at chromosome 20 and their association with recurrence in gastric cancer patients
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Attenuation of telomerase activity by hammerhead ribozyme targeting human telomerase RNA induces growth retardation and apoptosis in human breast tumor cells
INTERNATIONAL JOURNAL OF CANCER 114:484~489,2005


Quantitative detection of telomerase activity by real-time TRAP assay in the body fluids of cancer patients.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 16 5:857~863,2005


cDNA 미세배열 비교게놈교잡법 (cDNA microarray-based comparative genomic hybridization)을 이용한 염색체 이상 질환의 최신 고속 산전 유전 진단
대한산부인과학회지(Korean Journal of Obstetrics and Gynecololy) 48 7:1621~1634,2005


Different role of functional domains of hTR in DNA binding to telomere and telomerase reconstruction
FEBS LETTERS 579:127~132,2005


제대혈 유래 CD34 양성세포로부터 적혈구 분화유도와 Microarray를 이용한유전자 프로파일 분석
대한진단검사의학회지 25 6:457~464,2005


Neoadjuvant chemotherapy with infusional 5-fluorouracil, adriamycin and cyclophosphamide (iFAC) in locally advanced breast cancer: an early response predicts good prognosis
ANNALS OF ONCOLOGY 16:1778~1785,2005


Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents
BIOCHEMICAL PHARMACOLOGY 70:13~21,2005


Systematic analysis of cDNA microarray-based CGH.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 17:261~267,2006


Induction of cell apoptosis in non-small cell lung cancer cells by cyclin A1 small interfering RNA
CANCER SCIENCE 97 10:1082~1092,2006


Long-term Survival after Surgical Resection for Liver Metastasis from Gastric Cancer: Two Case Reports
CANCER RESEARCH AND TREATMENT 38 3:184~188,2006


Significant Gene Selection Using Integrated Microarray Data Set with Batch Effect
GENOMICS & INFORMATICS 4 3:110~117,2006


Activation of hypoxia-inducible factor-1α is necessary for lysophosphatidic acid-induced vascular endothelial growth factor expression
CLINICAL CANCER RESEARCH 12 21:6351~6358,2006


Alteration of hTERT full-length variant expression level showed different gene expression profiles and genomic copy number changes in breast cancer.
ONCOLOGY REPORTS 15:749~755,2006


Ribonucleotide reductase M1 (RRM1) 2464G > A polymorphism shows an association with gemcitabine chemosensitivity in cancer cell lines
PHARMACOGENETICS AND GENOMICS 16:429~438,2006


유방암의 전신적 재발로 오인된 톡소플라스마증 1예
대한내과학회지(korean Journal of medcine) 71 1:108~113,2006


Intermediate dose 5-fluorouracil-induced encephalopathy
JAPANESE JOURNAL OF CLINICAL ONCOLOGY 36:55~59,2006


A phase II study of infusional 5-fluorouracil and low-dose leucovorin with docetaxel for advanced gastric cancer
ONCOLOGY 70:63~70,2006


A phase II trial of S-1 monotherapy in metastatic colorectal cancer after failure of irinotecan- and oxaliplatin-containing regimens
BRITISH JOURNAL OF CANCER 95:1637~1641,2006


Entropy-based analysis of the non-linear relationship between gene expression profiles of amplified and non-amplified RNA
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 20 6:905~912,2007


A comparative study of volumetric analysis, histopathologic downstaging, and tumor regression grade in evaluating tumor response in locally advanced rectal cancer following preoperative chemoradiation
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 67 1:204~210,2007


Role of(18)F-Fluorodeoxyglucose positron Emission Tomography in detecting Extrahepatic Metastasisin pretreatment staging of hin pretreatment staging of hepatocellular carcinoma
ONCOLOGY 72 S1:104~110,2007


Gastrointestinal stromal tumor of the rectum: An analysis of seven cases
SURGERY TODAY 37 6:455~459,2007


Prognostic impact of resection margin involvement after extended (D2/D3) gastrectomy for advanced gastric cancer: A 15-year experience at a single Institute
JOURNAL OF SURGICAL ONCOLOGY 95:461~468,2007


The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation
ONCOGENE 26 6:934~944,2007


Clinical role of bone marrow angiogenesis in childhood acute lymphocytic leukemia
YONSEI MEDICAL JOURNAL 48 2:171~175,2007


The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas
LABORATORY INVESTIGATION 87 7:644~650,2007


Genome-wide genetic aberrations of thymoma using cDNA microarray based comparative genomic hybridization
BMC GENOMICS 8:749~754,2007


A Locally Advanced Breast Cancer with Difficult Differential Diagnosis of Carcinosarcoma and Atypical Medullary Carcinoma, which had Poor Response to Adriamycin- and ...
BREAST CANCER RESEARCH AND TREATMENT 39 3:134~137,2007


Putative chemosensitivity predictive genes in colorectal cancer cell lines for anticancer agents
ONCOLOGY REPORTS 18:593~599,2007


Integrated in silico and biological validation of the blocking effect of C(o)t-1 DNA on microarray-CGH
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 19:901~908,2007


An Attempt for Combining Microarray Data Sets by Adjusting Gene Expressions
Cancer Research and Treatment 39 2:74~81,2007


Novel and simple transformation algorithm for combining microarray data sets
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A phase II trial of weekly fractionated irinotecan and cisplatin for advanced gastric cancer
CANCER CHEMOTHERAPY AND PHARMACOLOGY 59:313~320,2007


A phase II study of S-1 monotherapy administered for 2 weeks of a 3-week cycle in advanced gastric cancer patients with poor performance status
BRITISH JOURNAL OF CANCER 97:458~463,2007


Molecular basis of the differences between normal and tumor tissues of gastric cancer
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Bilateral breast cancer: Differential diagnosis using histological and biological parameters
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Irofulven as first line therapy in recurrent or metastatic gastric cancer: a phase II multicenter study by the Cancer Therapeutics Research Group (CTRG)
CANCER CHEMOTHERAPY AND PHARMACOLOGY 59:295~300,2007


Identification of genes with correlated patterns of variations in DNA copy number and gene expression level in gastric cancer
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Different criteria for HER2 positivity by IHC can be applied in post-chemotherapy specimens in determining HER2 as a prognosticator in locally advanced breast cancer
BREAST CANCER RESEARCH AND TREATMENT 104:31~37,2007


An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients
ONCOLOGIST 12:622~630,2007


Changing patterns of prognosticators during 15-year follow-up of advanced gastric cancer after radical gastrectomy and adjuvant chemotherapy: A 15-year follow-up study at a single korean institute
ANNALS OF SURGICAL ONCOLOGY 14:2730~2737,2007


Whole genome analysis for liver metastasis gene signatures in colorectal cancer
INTERNATIONAL JOURNAL OF CANCER 121:2005~2012,2007


Multi-institutional phase II study of S-1 monotherapy in advanced gastric cancer with pharmacokinetic and pharmacogenomic evaluations
ONCOLOGIST 12 5:543~554,2007


Cetuximab rescue a patient with non-small cell lung cancer from rapid disease progression during chemotherapy
ACTA ONCOLOGICA 46 4:547~549,2007


Variation of the 3 ` telomeric overhang lengths in human cells
Cancer Letters 264:107~118,2008


Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer
Breast Cancer Research And Treatment 108:241~250,2008


Phase I trial of neoadjuvant concurrent chemoradiotherapy with S-1 and weekly irinotecan in locally advanced rectal cancer
Radiotherapy And Oncology 87:361~366,2008


Capecitabine and doxorubicin combination chemotherapy as salvage therapy in pretreated advanced gastric cancer
Cancer Chemotherapy And Pharmacology 61:157~165,2008


The combination of capecitabine and irinotecan in treating 5-Fluorouracil- and Oxaliplatin-pretreated metastatic colorectal cancer
Cancer Chemotherapy And Pharmacology 61:75~81,2008


A phase II study of paclitaxel combined with infusional 5-fluorouracil and low-dose leucovorin for advanced gastric cancer
Cancer Chemotherapy And Pharmacology 61:315~321,2008


Phase III trial of adjuvant 5-fluorouracil and adriamycin versus 5-fluorouracil, adriamycin, and polyadenylic-polyuridylic acid (poly A : U) for locally advanced gastric cancer after curative surgery: final results of 15-year follow-up
Annals Of Oncology 19:520~526,2008


Survival benefit of combined curative resection of the stomach (D2 resection) and liver in gastric cancer patients with liver metastases
Annals Of Oncology 19:1146~1153,2008


Improving the prediction accuracy in classification using the combined data sets by ranks of gene expressions
Bmc Bioinformatics 9:~,2008


Mobilized CD34+ cells as a biomarker candidate for the efficacy of combined maximal tolerance dose and continuous infusional chemotherapy and G-CSF surge in gastric cancer
Cancer Letters 270 2:269~276,2008


Inhibition of gastric cancer invasion and metastasis by PLA2G2A, a novel beta-catenin/TCF target gene
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OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation
PLoS One 3 8:~,2008


SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis
Bmc Bioinformatics 9 0:0~0,2008


S-1 Monotherapy as a Neoadjuvant Treatment for Locally Advanced Gastric Cancer
The Korean Journal Of Internal Medicine 23 1:37~41,2008


Angiogenic factor thymidine phosphorylase increases cancer cell invasion activity in patients with gastric adenocarcinoma
Molecular Cancer Research 6 10:1554~1566,2008


Cyclooxygenase-2 Expression in Pretreatment Biopsy as a Predictor of Tumor Responses After Preoperative Chemoradiation in Rectal Cancer
Archives Of Surgery 143:1091~1097,2008


Phase II study of combination chemotherapy of 5-fluorouracil, low-dose leucovorin, and oxaliplatin (FLOX regimen) in pretreated advanced gastric cancer
Annals Of Oncology 19 6:1135~1140,2008


Disease Prediction Using Ranks of Gene Expressions
Genomics & Informatics 6 3:136~141,2008


In vitro pharmacogenomic database and chemosensitivity predictive genes in gastric cancer
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Association of the ABCB1 gene polymorphisms 2677G > T/A and 3435C > T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients
Annals Of Oncology 20 2:272~277,2009


Postoperative adjuvant chemotherapy of gastric cancer: scrutiny into the clinical evidence based on quality assessment of medical literature of randomized controlled trials
CANCER CHEMOTHERAPY AND PHARMACOLOGY 63 5:919~927,2009


G-T haplotype (2677G > T/A and 3435C > T) of ABCB1 gene polymorphisms is associated with ethnic differences to paclitaxel sensitivity in cancer cells with different gene expression pattern
Cancer Letters 277 2:155~163,2009


The Effect of Spleen-Preserving Lymphadenectomy on Surgical Outcomes of Locally Advanced Proximal Gastric Cancer
Journal Of Surgical Oncology 99:275~280,2009


Effect of being overweight on postoperative morbidity and long-term surgical outcomes in proximal gastric carcinoma
Journal Of Gastroenterology And Hepatology 24 3:475~479,2009


Prediction of high-risk patients by genome-wide copy number alterations from remaining cancer after neoadjuvant chemotherapy and surgery
International Journal Of Oncology 34:837~846,2009


Copy number changes can be a predictor for hemoglobin reduction after S-1 monotherapy in gastric cancer
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Subtelomeric DNA methylation and telomere length in human cancer cells
Cancer Letters 281 1:82~91,2009


Prediction of recurrence of early gastric cancer after curative resection
Annals Of Surgical Oncology 16 7:1896~1902,2009


A weighted sample size for microarray datasets that considers the variability of variance and multiplicity
Journal Of Bioscience And Bioengineering 108 3:252~258,2009


Identification of significant regional genetic variations using continuous CNV values in aCGH data
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Promoter Methylation of the Wnt/beta-Catenin Signaling Antagonist Dkk-3 Is Associated With Poor Survival in Gastric Cancer
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DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers
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Phospholipase c delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer
Oncogene 28 26:2466~2475,2009


Phase I and pharmacokinetic study of cisplatin and troxacitabine administered intravenously every 28 days in patients with advanced solid malignancies
CANCER CHEMOTHERAPY AND PHARMACOLOGY 65 1:167~175,2009


Benefits of recurrent colonic stent insertion in a patient with advanced gastric cancer with carcinomatosis causing colonic obstruction
Yonsei Medical Journal 50 2:296~299,2009


oncogenic pathway combinations predict clinical prognosis in gastric cancer
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Treatment outcomes of sunitinib treatment in advanced renal cell carcinoma patients: a single cancer center experience in korea
Cancer Research And Treatment 41 2:67~72,2009


Prognosis of pN3 stage gastric cancer
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clinical value of ezrin expression in primary osteosarcoma
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Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma
Annals Of Oncology 20 4:780~787,2009


Increments of alpha-dystroglycan expression in liver metastasis correlate with poor survival in gastric cancer
Journal Of Surgical Oncology 100 6:459~465,2009


A Phase II Feasibility Study of Weekly Paclitaxel in Heavily Pretreated Advanced Gastric Cancer Patients with Poor Performance Status
Oncology 77 6:349~357,2009


Docetaxel versus Paclitaxel Combined with 5-FU and Leucovorin in Advanced Gastric Cancer: Combined Analysis of Two Phase II Trials
Cancer Research And Treatment 41 4:196~204,2009


Changes of Telomerase Activity by Alternative Splicing of Full-Length and beta Variants of hTERT in Breast Cancer Patients
Oncology Research 18 5-6:213~220,2009


Prognostic index reflecting genetic alteration related to disease-free time for gastric cancer patient
Oncology Reports 22 2:421~431,2009


Circulating endothelial progenitor cells (EPC) for tumor vasculogenesis in gastric cancer patients
Cancer Letters 288 1:124~132,2010


Two Dosages of Oral Fluoropyrimidine S-1 of 35 and 40 mg/m(2) bid: Comparison of the Pharmacokinetic Profiles in Korean Patients with Advanced Gastric Cancer
JAPANESE JOURNAL OF CLINICAL ONCOLOGY 40 1:29~35,2010


Association of the ABCB1 3435C>T polymorphism and treatment outcomes in advanced gastric cancer patients treated with paclitaxel-based chemotherapy
Oncology Reports 23:271~278,2010


A Phase II Study of a Combined Biweekly Irinotecan and Monthly Cisplatin Treatment for Metastatic or Recurrent Gastric Cancer
American Journal of Clinical Oncology-Cancer Clinical Trials 33 1:56~60,2010


Identification of genes related to a synergistic effect of taxane and suberoylanilide hydroxamic acid combination treatment in gastric cancer cells
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 136 12:1901~1913,2010


The clinical significance of ascitic fluid CEA in advanced gastric cancer with ascites
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 136:517~526,2010


Phase II study of preoperative chemoradiotherapy (CRT) with irinotecan plus S-1 in locally advanced rectal cancer
Radiotherapy And Oncology 95 3:303~307,2010


Adenocarcinoma of the small bowel at a single Korean institute: management and prognosticators
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 136 3:387~394,2010


Outcomes of multiple salvage chemotherapy for advanced gastric cancer: implications for clinical practice and trial design
CANCER CHEMOTHERAPY AND PHARMACOLOGY 66 4:797~805,2010


A phase I pharmacokinetic and pharmacodynamic study of CKD-732, an antiangiogenic agent, in patients with refractory solid cancer
Investigational New Drugs 28 5:650~658,2010


Molecular characterization of alternative SET-NUP214 fusion transcripts in a case of acute undifferentiated leukemia
Cancer Genetics and Cytogenetics 201 2:73~80,2010


Chemokine growth-regulated oncogene 1 as a putative biomarker for gastric cancer progression
Cancer Science 101 10:2200~2206,2010


Identification of novel gastric cancer-associated CNVs by integrated analysis of microarray
Journal Of Surgical Oncology 102 5:454~461,2010


Efficacy and feasibility of radiofrequency ablation for liver metastases from gastric adenocarcinoma
International Journal Of Hyperthermia 26 4:305~315,2010


Wernicke’s Encephalopathy in Advanced Gastric Cancer
Cancer Research and Treatment 42 2:77~81,2010


Green Tea Consumption and Stomach Cancer Risk: A Meta-Analysis
Epidemiology and Health 32:~,2010


The Clinical Outcome of Chemotherapy-Induced Amenorrhea in Premenopausal Young Patients with Breast Cancer with Long-Term Follow-up
Annals of Surgical Oncology 17 12:3259~3268,2010


Novel Sunitinib Strategy in Metastatic Renal Cell Carcinoma on Hemodialysis: Intermittent Dose of Sunitinib after Hemodialysis
Cancer Research and Treatment 42 3:180~184,2010


Clinicopathologic Features of Metachronous or Synchronous Gastric Cancer Patients with Three or More Primary Sites
Cancer Research and Treatment 42 4:217~224,2010


Brain metastases from colorectal carcinoma: prognostic factors and outcome
JOURNAL OF NEURO-ONCOLOGY 101:49~55,2011


Identification of genes associated with chemosensitivity to SAHA/taxane combination treatment in taxane-resistant breast cancer cells
BREAST CANCER RESEARCH AND TREATMENT 125 1:55~63,2011


Genome-wide molecular characterization of mucinous colorectal adenocarcinoma using cDNA microarray analysis
ONCOLOGY REPORTS 25 3:717~727,2011


Prevalence and associated factors of psychological distress among Korean cancer patients
GENERAL HOSPITAL PSYCHIATRY 33 3:246~252,2011


Gadoxetate disodium-enhanced hepatobiliary phase MRI of hepatocellular carcinoma: correlation with histological characteristics
AMERICAN JOURNAL OF ROENTGENOLOGY 197 2:399~405,2011


Economic and patient-reported outcomes of outpatient home-based versus inpatient hospital-based chemotherapy for patients with colorectal cancer
SUPPORTIVE CARE IN CANCER 19 7:971~978,2011


A Randomized Phase 2 Study of Docetaxel and S-1 Versus Docetaxel and Cisplatin in Advanced Gastric Cancer With an Evaluation of SPARC Expression for Personalized Therapy
CANCER 117 10:2050~2057,2011


Predictive values of 5-fluorouracil pathway genes for S-1 treatment in patients with advanced gastric cancer
ANTI-CANCER DRUGS 22 8:801~810,2011



2011/10/18 08:52 2011/10/18 08:52
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