사용자 삽입 이미지
[조선-전문의 칼럼] 채현욱교수 - 성장호르몬 치료의 오해와 진실

의학적으로 '성장곡선상에서 표준편차가 -2 이하일 때' 또는 '100명 중 하위 3 이하일 때' 저신장으로 판명된다. 좀 더 쉬운 표현으로 바꿔 말하면 키가 또래 평균보다 10㎝ 이상 작거나 1년에 4㎝ 이하로 자라는 아이의 경우 저신장 가능성이 있다고 볼 수 있다. 이때 찾게 되는 게 '성장호르몬 주사'다. 하지만 성장호르몬 주사 요법이 누구에게나 효과적인 건 아니다.

각종 성장장애(성장호르몬결핍증·터너증후군·신부전증·누난증후군)를 앓고 있는 아이에게 성장호르몬 치료는 필수적이다. 그 밖에 △예상 키가 매우 작은 경우 △키 때문에 심리적 어려움을 겪는 경우 △원인 불명의 특발성 저신장인 경우 △유전적 저신장으로 고통받는 경우 등에도 성장호르몬 치료를 고려할 수 있다.

성장호르몬 치료와 관련, 가장 많이 받는 질문은 크게 세 가지다. 첫째, '성장호르몬 주입 방식은 주사 요법이 유일한가' 하는 것이다. 정답은 '그렇다'다. 성장호르몬은 아미노산으로 이뤄진 단백질 기반의 펩티드 호르몬이어서 먹으면 위에서 파괴돼버린다. 따라서 현재까진 주사제 형태로만 개발돼 있다.

둘째, '부작용은 없는가' 하는 것이다. 정답은 '거의 없다'다. 예전에 사용되던 '사체 추출' 성장호르몬은 감염 등에 따른 문제점이 보고되기도 했다. 하지만 요즘 사용되는 성장호르몬에선 이 같은 부작용이 없다. 백혈병·뇌종양 발생과의 관련성도 적은 것으로 파악되고 있다. 간혹 △접종 부위 통증 △근육(관절)통 △두통 △혈당 증가 등 부작용이 있을 수 있지만 대개는 일시적이며 주사를 중단하면 곧바로 회복된다. 또한 환자는 치료 기간 동안 성장판·호르몬 검사 등을 정기적으로 시행한 후 부작용 여부를 확인하게 된다.

셋째, '치료를 받으면 원래 클 키가 미리 자란 후 더 이상 안 크는 게 아닌가' 하는 것이다. 정답은 '아니다'다. 간혹 그렇게 보이는 경우가 있다 해도 대개는 이미 사춘기에 접어든 이후 병원을 찾는 환자로 인해 나타나는 '착시 현상'일 뿐이다. 성장호르몬 치료는 뒤처진 성장 속도를 끌어올려 최종 키 형성에 도움을 주는 역할을 한다.

일반적으로 성장호르몬 치료는 △저신장 정도가 심할수록 △어린 나이에 시작할수록 △치료 기간이 길수록 효과가 좋은 것으로 알려져 있다. 다만 어떤 환자가 치료에 얼마나 반응하는지 예측하긴 어렵다. 반응이 좋은 환자 중엔 2년 이상 치료해 (최종 신장을 기준으로 했을 때) 적게는 5㎝, 많게는 7㎝까지 더 자란 사례도 있다.

현재 성장호르몬 치료는 주 6회에서 7회 주사하는 방법이 가장 널리 쓰인다. 요즘은 주삿바늘이 숨겨져 있고 투약 용량 자동 조절 기능을 갖춘 전자식 기기가 나와 있어 한결 간편해졌다.


조선일보 기사원문 바로가기
강남세브란스병원 소아청소년과 바로가기 


이올린에 북마크하기(0) 이올린에 추천하기(0)
2012/11/01 08:46 2012/11/01 08:46

댓글을 달아 주세요

댓글 RSS 주소 : http://blog.iseverance.com/P1/rss/comment/25
댓글 ATOM 주소 : http://blog.iseverance.com/P1/atom/comment/25
  1. Porn Sites 2012/11/16 10:49  댓글주소  수정/삭제  댓글쓰기

    I tend not to write many remarks, however i did some searching and wound up here [강남]소아청소년과 블로그.

    And I do have a couple of questions for you if it's allright. Is it only me or does it look as if like a few of these responses look like coming from brain dead visitors? :-P And, if you are posting at other sites, I would like to follow everything new you have to post. Would you list of all of your community sites like your twitter feed, Facebook page or linkedin profile?

  2. online casino 2012/12/24 17:41  댓글주소  수정/삭제  댓글쓰기

    Hello, i think that i saw you visited my blog
    so i came to “return the favor”.I am attempting to find things to improve my site!
    I suppose its ok to use a few of your ideas!!

  3. payday loan 2013/04/06 12:15  댓글주소  수정/삭제  댓글쓰기

    Everybody experiences emergencies every now and then.
    Unfortunately, many of us are incredibly strapped for cash that individuals
    don’t have the funds to help all of us out there of these
    times of need. It isn’t really that easy to just go to
    the bank and remove an individual loan to assist pay that will electricity expenses.
    Occasionally you simply need a little bit of extra money
    to truly get you through to the next short term.

    payday loan
    Luckily, that is where Pay day loans Say yes to is available
    in. We are not really loan companies, we provide you using a means
    of System.Drawing.Bitmap achievable loan that will provide what you need.
    By completing our own simple and easy application form, Pay day loans Say yes
    to can match you along with certainly one of our set up, well-known partners so that you can obtain the mortgage which
    is ideal to you. Think about all of us because the “middle-man” - all
    of us consider all the guesswork and decision-making out of the process.
    Merely complete the form, and we go with a person using a appropriate loan
    provider. It is that easy!
    payday loan

  4. Marietta 2013/04/19 11:30  댓글주소  수정/삭제  댓글쓰기

    wiedziona łakomstwem rzuciła si? na fant Marietta r?wnie? zbyt nie przygl?dała.
    Post?kuj?c
    przysiadł, ustawił sumiennie przyn?t?. Pocz?ł pełza? nazad, rozwijaj?c za sob? wydłu?ony s.

  5. marginalisation 2013/04/19 11:31  댓글주소  수정/삭제  댓글쓰기

    t?w przy
    r?k?, rzuciła w niego obwarzankiem. marginalisation I owszem byczy, pomy?lał, i? nie załatwia w sam raz
    kramu rybnego. Rozrywka udała si?
    z okładem ka?de oczekiwania, resztkami
    sił dwie przecznice znaczniej widzi.

  6. Stacie 2013/04/19 11:36  댓글주소  수정/삭제  댓글쓰기

    . Urwał, zakłopotany. Rycerz spojrzał
    pytaj?co. - I? Stacie takim sposobem. M?wili, ze rycerz powinien
    w zbroi na besti? p?j??, kopi? przygani?,
    zatratowa? ku
    du?ej chwale bo?ej. Oraz tak bardzo,

  7. tobacconists 2013/05/13 04:37  댓글주소  수정/삭제  댓글쓰기

    cz?ł broszurowa? sk?r?
    wprawnymi ruchami. Arnold przygl?dał tobacconists si? spo?r?d zainteresowaniem.
    - Zr?cznie wam truchta spo?r?d t??e dratw? - zauwa?ył.
    Rycerz o
    odrobin? nie zakłuł si? w palec. Poruszył znad ?c.

  8. Toby 2013/05/13 18:01  댓글주소  수정/삭제  댓글쓰기

    maj?c do wszechpot?gi owce, połaszczyłby si? na łykowate, Toby
    zasuszone dziewice. - W sam raz - przynaglił
    Arnolda, kto wymrukiwał pod nosem jakie? przekle?stwa.
    - Powiadasz, ?e oficjalnie g.

  9. Rena 2013/05/13 18:01  댓글주소  수정/삭제  댓글쓰기

    aj? do?? plugawej bestii i Rena z zapałem
    schroni?
    przedtem kr?lewskim gniewem przeci?tnego, kto miasteczko od czasu niej uwolni.
    Chocia? fuks poseł zarzekał si?, i? owo zgodno?? z rzeczywisto?ci?, i dodatkowo
    jacy? przedtem ustalone, jacy?.

  10. Hellen 2013/05/21 02:41  댓글주소  수정/삭제  댓글쓰기

    Zarówno w Hellen części czołowej, owych środków komunikacji
    miejskiej mamy pięcio. Będą to autobusy, tramwaje Hellen,
    szybka kolej miejska, tramwaj wodny plus – Hellen
    coś nowemu.

  11. 근돌이 2013/05/31 10:28  댓글주소  수정/삭제  댓글쓰기

    본문에 '적게는 5cm, 많게는 7cm까지 더 자란 사례도 있다'고 하셨는데 제가 궁금한건, 5cm ~ 7cm가 '더' 자랐다는걸 어떻게 확인할 수 있냐는겁니다. 성장호르몬 주사를 맞지 않았을 경우 자연적으로 얼만큼 컸을지는 결국 확신할 수 없는 거 아닌가요?

  12. Ernie 2013/06/08 22:18  댓글주소  수정/삭제  댓글쓰기

    zyżak. - Aktualnie w dzisiejszych czasach suknem lambswool (Ernie) walą, potężnym, czerwonym.

    Aż spośród Gdańska sprowadzałem, nie zna
    owo być, iżbyś skonał, panie, na wskutek tego suknie, na jakim mieszczan ścinają.
    .. - A więc to ju�.

  13. theweddingfavors.wikidot.com 2014/05/30 00:17  댓글주소  수정/삭제  댓글쓰기

    Howdy! Someone in my Myspace group shared this website with us so I came to take a look.
    I'm definitely loving the information. I'm book-marking and will be tweeting
    this to my followers! Outstanding blog and amazing design and style.

  14. joshpellicerbook 2014/05/31 22:13  댓글주소  수정/삭제  댓글쓰기

    Does your website have a contact page? I'm
    having problems locating it but, I'd like to send you an e-mail.
    I've got some recommendations for your blog you might
    be interested in hearing. Either way, great website and I look forward to seeing it grow over time.

  15. josh pellicer book 2014/05/31 22:20  댓글주소  수정/삭제  댓글쓰기

    Hey I know this is off topic but I was wondering if you knew of any widgets I could add to my blog that automatically tweet my newest twitter updates.
    I've been looking for a plug-in like this for quite
    some time and was hoping maybe you would have some experience with something like this.
    Please let me know if you run into anything. I truly enjoy reading your blog and I look forward
    to your new updates.

  16. Torrance Realtor 2014/10/01 08:03  댓글주소  수정/삭제  댓글쓰기

    These are in fact wonderful ideas in on the topic of blogging.

    You have touched some fastidious points here. Any way keep up wrinting.

  17. Projekt 2014/10/07 23:39  댓글주소  수정/삭제  댓글쓰기

    If you are going for most excellent contents like I do, just go to see this
    web site all the time as it offers feature contents, thanks

  18. cream Creambath 2015/11/30 09:28  댓글주소  수정/삭제  댓글쓰기

    Yes! Finally someone writews about simulatorul.

  19. seo 2016/03/19 00:10  댓글주소  수정/삭제  댓글쓰기

    Thanks , I have just been looking for information approximately this topic for ages and yours
    is the best I have discovered so far. But,
    what in regards to the bottom line? Are you certain concerning the supply?

  20. blogigo.com 2016/03/29 18:00  댓글주소  수정/삭제  댓글쓰기

    Hi there, yeah this piece of writing is really
    pleasant and I have learned lot of things from it regarding blogging.

    thanks.

  21. avant loans review 2016/06/17 00:18  댓글주소  수정/삭제  댓글쓰기

    This website certainly has all of the information I needed concerning this subject and didn't know who to ask.

  22. m.crewknowledge.com 2016/07/04 23:49  댓글주소  수정/삭제  댓글쓰기

    Delegation - Successful brokers have great support teams
    in place because they realize can't do it all alone. Watch all the real estate investor
    guru's advertising. Some of the considerations on which a
    professional can advise you include the results of
    home inspections on a house you're considering; infrastructure (city water versus well, septic system
    versus sewer, and so forth); and structural details of
    a given home which may either add to or detract from the value of the house.

  23. Chanel 2016/07/05 00:34  댓글주소  수정/삭제  댓글쓰기

    After you get closer to choosing your apartment
    home, look at your list to make sure its want you wanted initially.
    Ensure you have sufficient cupboard space to hide away the everyday detritus that
    few of us can live without. If you have narrowed your options to a home that happens to
    be staged, the first thing you should do is view the property a few times.

  24. 所沢 脱毛 2016/07/08 21:48  댓글주소  수정/삭제  댓글쓰기

    昔を思えば、ワキ脱毛もハードルが低くなりました。そこにあるのは、ワキ脱毛を脱毛の第一段階的な位置づけに設定していて何はともあれ安心価格で体験してもらおうと目論んでいるからなのです。

  25. 脱毛サロン 料金 2016/07/11 09:21  댓글주소  수정/삭제  댓글쓰기

    今の時代の脱毛は、1人でムダ毛の対処をするのとは違って、脱毛エステサロンまたは皮膚科などに依頼して施術するというのが一般的と言えます。

  26. car servicing 2016/07/12 16:57  댓글주소  수정/삭제  댓글쓰기

    Write more, thats all I have to say. Literally, it seems as
    though you relied on the video to make your point.
    You obviously know what youre talking about, why throw away your intelligence on just posting videos to your site when you could be giving us something
    enlightening to read?

  27. Alda 2016/07/24 11:56  댓글주소  수정/삭제  댓글쓰기

    Thank you for your blog post. Thomas andd I are saing
    for our new guide on this subject annd your article has made us all to save the
    money. Your notions really answered all our problems.
    In fact, more than what we had acknowledged just before we found your superb blog.
    I actually no longer nurture doubts and a troubled mind
    because you have totally attended to our needs in this article.
    Thanks

  28. sports t shirts 2016/09/16 20:47  댓글주소  수정/삭제  댓글쓰기

    It's difficult to find knowledgeable people in this particular
    topic, however, you seem like you know what you're talking about!

    Thanks

  29. junk car buyer austin austin tx 2016/11/25 21:49  댓글주소  수정/삭제  댓글쓰기

    BMW dealers maҝe a profit fгom tһese breakdowns,
    the independent shops Ԁo not know hⲟԝ to repair tһese junk eitɦeг.

  30. racing movies on netflix instant 2016/12/17 12:01  댓글주소  수정/삭제  댓글쓰기

    Senna's competition with one-time teammate Alain Prost can be a significant target of
    the documentary, along side the unfortunately prescient initiatives of Senna to increase Formula One racing's safety.

  31. life insurance definition 2016/12/17 22:07  댓글주소  수정/삭제  댓글쓰기

    Unlike other online learning resources on the market that overcalculate your life insurance policy to sell
    a larger quality to you, we at NerdWallet promise to advocate merely what you need.

  32. fibre optic cable specification 2016/12/26 23:27  댓글주소  수정/삭제  댓글쓰기

    Generally, the noise resources in a fiber optic link include disturbance in the RF amplifiers in the laser diode,
    the transmitter, the photodiode and RF amplifiers in the radio.

  33. enterprises car sales 2016/12/26 23:33  댓글주소  수정/삭제  댓글쓰기

    Promotional meetings were formerly suspended by it and taking applications from future new sales associates.

  34. bed bugs bites 2017/01/19 01:59  댓글주소  수정/삭제  댓글쓰기

    But, you'll be able to reduce your likelihood of a bed bug infestation that is
    costly by capturing them early.

  35. Art Slominski 2017/02/14 20:52  댓글주소  수정/삭제  댓글쓰기

    Hi, i think that i saw you visited my blog so i came to ?return the favor?.I'm trying to find things to improve my website!I suppose its ok to use a few of your ideas!!

  36. steroids buy forum 2017/02/22 07:47  댓글주소  수정/삭제  댓글쓰기

    Buy Anabolic Steroids Online ,online steroid shop reviews,online steroid shop uk,online steroid shopping,online steroid shop south
    africa,online steroid shop australia,steroid online shop malaysia,steroid online shop singapore,best online
    steroids shop,australian online steroid shop,legit,online steroid shops,best online steroid shop uk,
    best online steroid shop reviews,best online steroid shop australia,
    reliable online steroid shop,anabolic steroids online shop in india,bodybuilding steroids online shopping india,online steroid shop in india,online steroid shop europe,steroid online shop indonesia,guter online steroid shop,steroid online shop erfahrung,steroid online shop bewertung,shop steroids online,best steroids shop online,steroids,online shop review,steroids shop online uk

  37. The Coolest Guy From China 2017/02/28 16:20  댓글주소  수정/삭제  댓글쓰기

    Its not my first time to pay a quick visit this website, i am browsing this site dailly
    and obtain pleasant data from here all the time.